Nxgen
Innovator Specialty Products
COMPOSITION
Each capsule of WEBACE contains Palbociclib 125 mg/ 100 mg / 75 mg for oral use.
INDICATION
Palbociclib is a CDK 4/ 6 kinase inhibitor indicated for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in combination with
(1) an aromatase inhibitor as initial endocrine-based therapy in postmenopausal women or in men
(2) Fulvestrant in patients with disease progression following endocrine therapy.
DOSAGE AND ADMINISTRATION
Webace capsules are taken orally with food in combination with an aromatase inhibitor or Fulvestrant. Recommended starting dose: 125 mg once daily, taken with food for 21 days followed by 7 days off treatment.
CONTRAINDICATIONS
None.
WARNINGS AND PRECAUTIONS
Neutropenia: Monitor complete blood count prior to the start of WEBACE therapy and at the beginning of each cycle, as well as on Day 15 of the first two cycles, and as clinically indicated. Embryo-Fetal Toxicity: WEBACE can cause fetal harm.
ADVERSE REACTIONS
Most common adverse reactions (incidence ≥10%) were neutropenia, infections, leukopenia, fatigue, nausea, stomatitis, anemia, alopecia, diarrhoea, thrombocytopenia, rash, vomiting, decreased appetite, asthenia, and pyrexia.
DRUG INTERACTIONS
1.CYP3A Inhibitors: Avoid concurrent use of WEBACE with strong CYP3A inhibitors. If the strong inhibitor cannot be avoided, reduce the WEBACE dose.
2.CYP3A Inducers: Avoid concurrent use of WEBACE with strong CYP3A inducers.
3.CYP3A Substrates: The dose of sensitive CYP3A4 substrates with narrow therapeutic indices may need to be reduced when given concurrently with WEBACE.
USE IN SPECIFIC POPULATIONS
Lactation: Advise not to breastfeed.
STORAGE:
Store at below 25°C, cool and dry place.
Webace Capsule 75mg
Product Information
Webace 75mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.
Webace Capsule 100mg
Product Information
Webace 100mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.
Webace Capsule 125mg
Product Information
Webace 125mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.
Docisol 80mg
Product Information
DOCISOL 80 contains Nanoparticle Docetaxel Lipid Suspension 80mg respectively. Docetaxel is an antineoplastic agent binds to free tubulin and promotes the assembly of tubulin into stable microtubules while simultaneously inhibiting their disassembly and cancer cell death.
Docisol 20mg
Product Information
DOCISOL 20 contains Nanoparticle Docetaxel Lipid Suspension 20mg respectively. Docetaxel is an antineoplastic agent binds to free tubulin and promotes the assembly of tubulin into stable microtubules while simultaneously inhibiting their disassembly and cancer cell death.
Abra Ace 100mg Injection
Product Information
ABRA-ACE for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin-bound), it belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, It works by stopping cell division and preventing the growth of certain cancer cells. Please refer our pack insert for further information.
Docisol 80mg
Product Information
DOCISOL 80 contains Nanoparticle Docetaxel Lipid Suspension 80mg respectively. Docetaxel is an antineoplastic agent binds to free tubulin and promotes the assembly of tubulin into stable microtubules while simultaneously inhibiting their disassembly and cancer cell death.
Docisol 20mg
Product Information
DOCISOL 20 contains Nanoparticle Docetaxel Lipid Suspension 20mg respectively. Docetaxel is an antineoplastic agent binds to free tubulin and promotes the assembly of tubulin into stable microtubules while simultaneously inhibiting their disassembly and cancer cell death.
Abra Ace 100mg Injection
Product Information
ABRA-ACE for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin-bound), it belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, It works by stopping cell division and preventing the growth of certain cancer cells. Please refer our pack insert for further information.
Webace Capsule 75mg
Product Information
Webace 75mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.
Webace Capsule 100mg
Product Information
Webace 100mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.
Webace Capsule 125mg
Product Information
Webace 125mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.
Webace Capsule 75mg
Product Information
DOCISOL 80 contains Nanoparticle Docetaxel Lipid Suspension 20 mg & 80 mg respectively. Docetaxel is an antineoplastic agent binds to free tubulin and promotes the assembly of tubulin into stable microtubules while simultaneously inhibiting their disassembly and cancer cell death.
Webace Capsule 100mg
Product Information
DOCISOL 20 contains Nanoparticle Docetaxel Lipid Suspension 20 mg & 80 mg respectively. Docetaxel is an antineoplastic agent binds to free tubulin and promotes the assembly of tubulin into stable microtubules while simultaneously inhibiting their disassembly and cancer cell death.
Webace Capsule 125mg
Product Information
ABRA-ACE for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin-bound), it belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, It works by stopping cell division and preventing the growth of certain cancer cells. Please refer our pack insert for further information.
